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Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma.

机译：只有影响p53的DNa结合域的错义突变才会影响乳腺癌患者的预后。

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Frédérique Végran; Magali Rebucci; Sandy Chevrier; Muriel Cadouot; Romain Boidot; Sarab Lizard-Nacol;
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1. Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53 [J] . Fei Zhou, Yanhua Zhang, Xiufang Xu, Cancer Cell International . 2018,第1期

机译：TP53 DNA结合域中具有相同错义突变的源自中国乳腺癌的三种稳定的Basal / HER2阳性乳腺癌细胞系的建立和表征
2. Establishment and characterization of a novel HPV-negative laryngeal squamous cell carcinoma cell line, FD-LSC-1, with missense and nonsense mutations of TP53 in the DNA-binding domain [J] . WuC.-P., ZhouL., GongH.-L., Cancer letters . 2014,第1期

机译：新型HPV阴性喉鳞状细胞癌细胞系FD-LSC-1的建立和鉴定，其DNA结合域中存在TP53的错义和无义突变
3. Missense mutations located in structural p53 DNA-binding motifs are associated with extremely poor survival in chronic lymphocytic leukemia. [J] . Trbusek M, Smardova J, Malcikova J, Journal of Clinical Oncology . 2011,第19期

机译：位于结构性p53 DNA结合基序中的错义突变与慢性淋巴细胞白血病的极差生存有关。
4. Distinguishing Driver Missense Mutations from Benign Polymorphisms in Breast Cancer [C] . Xiyu Zhang, Ruoqing Xu, Yannan Bin, International conference on intelligent computing . 2019

机译：从乳腺癌的良性多态性区分驾驶员错义突变。
5. Clinical implications of mutations in thep53 tumor suppressor gene in female patients with breast cancer. [D] . Lai, Hong Chen. 2002

机译：女性乳腺癌女性患者p53抑癌基因突变的临床意义。
6. Only Missense Mutations Affecting the DNA Binding Domain of P53 Influence Outcomes in Patients with Breast Carcinoma [O] . Frédérique Végran, Magali Rebucci, Sandy Chevrier, 2010

机译：影响乳腺癌患者P53 DNA结合域的影响的唯一错义突变。
7. Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53 [O] . Fei Zhou, Yanhua Zhang, Xiufang Xu, 2018

机译：三种稳定基底/海绵/海绵乳腺癌细胞系的建立与表征来自TP53的DNA结合结构域中具有相同畸变突变的乳腺癌

Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma.

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